CBDV (Cannabidivarin) is a cannabinoid that can be found in the cannabis plant. It is chemically similar to CBD but has a different side chain.
Unlike CBD, which comprises a pentyl side chain, CBDV contains a propyl side chain. It makes it more suited for interacting with specific brain receptors.
Legal in all 50 states
CBDV is a cannabinoid found in the cannabis plant. So, what is CBDV good at? It is non-psychoactive and offers several user benefits, including reducing social anxiety and pain relief.
The legality of CBD and marijuana products differs from state to state, and it is up to each individual to determine whether it is legal in their area. However, CBD products are generally safe if they contain less than 0.3 percent THC.
Marijuana plants produce mid to high levels of THC, the primary psychoactive compound in the plant that causes euphoria and gives users the “high” effect. It makes marijuana a Schedule I drug, similar to heroin and fentanyl.
Hemp is a different type of plant that produces moderate to low levels of THC. It was legalized on the federal level in 2018 under the Farm Bill. It makes hemp-derived CBD legally available in all 50 states.
Cannabinoid found in the cannabis plant
CBDV is a non-psychotropic homolog of cannabidiol, one of the essential cannabinoids in the cannabis plant. However, its chemical structure is so similar to CBD that it can be challenging to differentiate them on lab tests.
CBDV tends to be more abundant in indica cultivars native to the northwest India region. Its effects are largely unknown, but it is thought to have anticonvulsant properties and may help reduce nausea.
It’s also being studied for its potential therapeutic use in autism spectrum disorder (ASD) and Rett syndrome. While more research is required, it has been shown to shift glutamate and GABA metabolites — markers of the brain’s excitatory-inhibitory systems — which can be beneficial in treating these disorders.
It’s also been found to be an effective anticonvulsant.
Chemically similar to CBD
Cannabidivarin (CBDV) is a chemically similar cannabinoid to CBD. In addition, they both share many similarities on a molecular level, including seven double-bond isomers and 30 stereoisomers with a side chain shortened by two methylene bridges.
However, on a more chemical level, they have a few differences that set them apart. For example, while CBD has a carboxylic acid precursor, CBDV starts life as a different chemical compound.
It makes it essential to note that the liver metabolizes both compounds differently. After absorption, CBD is rapidly hydroxylated in the liver, which is further metabolized by the cytochrome P450 system.
This process allows it to bind with the CB1 and CB2 receptors in the endocannabinoid system to produce various effects. In particular, it’s used to reduce anxiety. It also helps with depression and other mental health disorders. In addition, it helps improve memory and mood in people with Rett syndrome. In addition, it can decrease gastrointestinal inflammation.
It is non-psychoactive
Despite its name, CBDV is not psychoactive and does not give you the same intoxicating effects as THC. Instead, users report that CBDV makes them feel calm and relaxed without inducing euphoria.
While CBDV research is still in its infancy, it is effective for helping with repetitive behavioral and communication issues, chemically-induced seizures, myotube production (muscle fiber formation), and inflammation. It may even help with Rett syndrome.
